Alzheimer's disease often begins many years before memory problems appear. During that silent phase, toxic changes slowly build inside the brain. For decades, scientists focused mostly on amyloid ...

Tau PET correlates closely with cognitive decline in Alzheimer’s disease, making it a potential surrogate outcome measure. Yet in amyloid immunotherapy trials to date, this signal has not always ...

He explained that Alzheimer’s involves a build-up of a protein, called amyloid, into plaques in the brain, followed by the development of tangles of tau protein years later. Cognitive symptoms start ...

Following the hard-won success of early anti-amyloid drugs, a new generation of Alzheimer’s modalities—from tau-targeting ...

Alzheimer’s disease affects millions, casting a shadow over families and communities, but recent advancements are lighting the way toward a brighter future. Researchers, scientists, and caregivers are ...

(CNN) — Increasing the number of steps you take every day may slow cognitive decline in older adults who already have biological signs of early Alzheimer’s disease, according to a new observational ...

This article is part of “Innovations In: Alzheimer's Disease” an editorially independent special report that was produced with financial support from Eisai. Alzheimer’s disease has proved to be a ...

If you are like a lot of people, you might be anxious about the risk of getting dementia as you age. The lifetime risk of ...

Microglial activation is a determining factor that allows amyloid-beta accumulation to drive reactive astrogliosis, amplifying inflammatory responses in the brain. This was the conclusion of a study ...