The adaptive immune system is an antigen-specific structure that discriminates non-self molecules through the recognition of peptide antigens using receptor interactions between T-cells and ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

The interferon regulatory factor (IRF) family of transcription factors, pivotal for initiating antiviral type I interferon ...

Tissue-resident macrophages are crucial players in the immune system, acting as the first line of defense and maintaining tissue homeostasis by responding to various environmental challenges and ...

Mariana Kaplan (Chief of the Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Health, USA) Mariana Kaplan, M.D., joined the ...

A newly discovered molecule may hold the key to rebalancing the immune system in lupus and autoimmune diseases. A newly discovered molecule may hold the key to rebalancing the immune system in lupus ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

Our immune systems develop to recognize what is foreign within our bodies. As immune cells are generated in the bone marrow and mature in other locations, they undergo processes that instruct which ...

One of the central components of the immune system is the enzyme cyclic GMP-AMP synthase (cGAS), which acts as a guard, detecting foreign DNA and initiating an immune response. If cGAS is not properly ...