Genetic modification of mammalian cells has vast use in biotherapeutics development and basic research applications. An important step early on is the isolation of clones with the desired mutation ...
In this interview, industry experts Mathieu Bennet and Dustin Whitson explore how automation and single-cell technologies are transforming high-throughput B-cell cloning for antibody discovery. Can ...
Single-cell cloning involves generating a cell line from a single initial cell isolated from a heterogeneous population, typically obtained through transfections, transductions, or primary cells ...