The optimization of assay parameters, such as invasion incubation time, the optimal time and multiplicity of infection (MOI) for Shigella invasion were determined using the balance between the Z’ ...

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic ...

Scientists led by Karla Satchell, Ph.D., the Anne Stewart Youmans Professor of Microbiology at Northwestern University, have discovered previously unknown molecular mechanisms that help a type of food ...

This trick allows the bacteria to make themselves at home in the host cell and avoid falling prey to the immune system. Working together with the University of Cologne structural biologists led by ...

Endosymbioses, where one organism lives within another, exist along a spectrum of interactions ranging from parasitic to mutualistic. Although many established endosymbioses are mutualistic, this need ...

Immune cells that eat bacteria in the body don't stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells ...

Researchers have found that specific gut cells, BEST4/CA7+ cells, regulate electrolyte and water balance in response to bacterial toxins that cause diarrhea. Their findings show that these cells ...

Jonathan Kotula: We think there needs to be a systems-level approach to deal with complex diseases such as cancer. A lot of what has been done so far are reductionist approaches—one small molecule for ...

Antibiotic persistence helps a small subpopulation of bacteria survive treatment without becoming genetically resistant, often leading to relapse and prolonged infection. Researchers are uncovering ...