Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

Scientists at St. Jude Children’s Research Hospital identified a protein network which locks ABCC4 transporters in place to maintain cyclic AMP signaling levels.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...