Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

Advancements in spatial proteomics enable detailed tissue mapping, linking protein localization to disease mechanisms and enhancing translational research.

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...