CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...

Using computer simulations, chemists have discovered how nuclear bodies called nucleoli interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets ...

Laura Rusche can speak to the media about a wide range of subjects in genomics and genetics. Her research focuses on chromatin and its impact on gene expression, genome stability and chromosome ...

AMES, Iowa – In their long strings of nucleotides, DNA molecules hold massive troves of genetic data providing instructions for how living organisms should function – the blueprint of life. How the ...

New findings shed light on how chromosomes manage the various pushing and pulling forces generated when cells divide. Specifically, researchers show that chromosomes resist being punctured by the ...

The nuclei of most human cells contains the entire genome, which would have a length of about six feet if it was fully extended. So this DNA has to be carefully compacted in cells, while still ...

New study shows that chromosomes of carnivores (cats, dogs and bears) show similar 3-D structures despite being separated by over 50 million years of evolution. Photo credits: Clouded leopard, ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Chromosomes are thread-like structures comprising DNA that are present inside the nucleus of every cell in the body. Specific segments of DNA are called genes. Every chromosome contains many genes, ...