The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Studies by researchers at Columbia University Irving Medical Center suggest that one of the immune system’s oldest branches, the complement system, and coagulation dysfunction, may be influencing the ...

Hemostasis is a complex system composed of many procoagulant and regulatory pathways. Multiple pathways, such as the intrinsic pathway, platelet activation and the tissue factor pathway, can affect ...

A novel class of antithrombotic medication, the factor XIa inhibitors, has had a rocky start but is powering through phase III trials, which are now underway. MedPage Today sat down to discuss the ...

Blood clotting can lead to life-threatening heart attacks and strokes, and current treatments can lead to excessive bleeding and other worrisome side effects. But researchers now say they've found a ...

February 6, 2007 (Seattle, WA) - Variants in key coagulation and anticoagulation proteins were more common in postmenopausal women who developed venous thrombosis (VT) than in those who did not, ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...

Stress Causes Lower INR in VTE Patients Not on Blood Thinners The effect of psychological distress on clotting times and clotting factors varies in patients with venous thromboembolism (VTE) and ...

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there's currently no cure. IBD ...

Drug resistance is defined as the lack of expected response to a standard therapeutic dose of a drug or as resistance resulting from biologic changes in the target, as occurs in antibiotic resistance.

Pathway to Cures, the venture philanthropy fund of the National Bleeding Disorders Foundation (NBDF), is pleased to announce its investment in SeraGene Therapeutics, a pioneering biotechnology company ...