Metal ions bridging the grooves of two DNA helices explain how they lock together, the first direct look at the DNA zipper ...

Researchers have captured the moment two DNA molecules zip together, overcoming their identical negative charges to pair up and revealing a mechanism that has puzzled scientists for more than 20 years ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

DNA replication and repair mechanisms constitute the foundation of genomic integrity, ensuring that genetic information is faithfully duplicated and maintained across cell generations. Replication ...

Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...