New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment ...

How do we find out which protein works in a particular DNA repair pathway? We know that if a DNA repair gene is mutated, cells become more sensitive to DNA damaging agents. Researchers in the 1960s ...

A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...

Scientists at Stanford University have discovered that DRT3, a unique defense system found in bacteria, creates DNA to ...

Researchers have introduced 'prime assembly,' a genome editing approach that allows insertion of large DNA segments, enabling entire gene replacements. The method avoids harmful double-strand breaks ...

Broken String Biosciences launched an early access program (EAP) through which select developers of gene edited therapeutics will be able to use Broken String’s INDUCE-seq ® technology in their own ...

Researchers at Genentech Inc. and UC Davis have worked out the structure of the RAD51 complex, which repairs breaks in DNA. When DNA experiences a double-strand break, enzymes trim back one of the two ...

When a gene is turned on in a cell, it creates a ripple effect along the DNA strand, changing the physical structure of the ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...

Delve into the field of PARP inhibitors, a class that has gained traction in ovarian, breast, and prostate cancers.