Ubiquitination of a subset of proteins by ubiquitin chain elongation factors (E4), represented by Ufd2p in Saccharomyces cerevisiae, is a pivotal regulator for many biological processes. However, the ...
Ubiquitination, sumoylation (tagging with small ubiquitin-like modifiers), ubiquitinated aggregates, and problems with ubiquitin-mediated proteasomal degradation have all been linked to pathological ...
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