Cellular findings show Telomir-Zn modulates intracellular metal balance linked to oxidative stress, mitochondrial ...

Genomic instability is a defining hallmark of cancer, underpinning tumor initiation, evolution, and progression. Increasingly, genomic instability itself is recognized not merely as a consequence of ...

A team of the University of Barcelona and the Biomedical Research Institute of Barcelona (IRB Barcelona) has designed a new bioinformatics tool to identify the chromosomal alterations that are ...

Hepta refractory multiple myeloma is marked by antigen loss, genomic complexity, and 12.8 month median survival in multi centre data.

In dysbiosis, an imbalance between beneficial and harmful gut bacteria reduces protective metabolites like short-chain fatty acids (SCFAs) and increases harmful substances, leading to systemic ...

Recently, the research team led by Prof. Junjiu Huang from Sun Yat-sen University, in collaboration with Prof. Fenghua Liu’s team at Guangdong Women and Children Hospital, published a study titled ...

Aging is a multifaceted process driven by interconnected biological mechanisms, among which genomic instability and telomere attrition stand as primary hallmarks. Emerging research underscores the ...

Accent Therapeutics launched a Phase I/II clinical trial last year to begin testing a small molecule inhibitor of KIF18A in ovarian cancers.

Powered by gene editing advances like CRISPR and base editing, cell and gene therapy (CGT) is delivering on the promise of genomic medicine. First-generation CAR T-cell therapies, for example, have ...

Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing whole chromosomes, changes that help tumors grow, adapt and resist treatment. In ...