A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

A new study led by Hartmut Geiger at the University of Ulm, Germany, and Yi Zheng and Kodandaramireddy Nalapareddy, Cincinnati Children's Hospital Medical Center (CCHMC), USA reveals that age-related ...

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes. That is wat ...

An international team of scientists based in the Netherlands, and in China, has found that intestinal cells can change specializations during their lives, driven by the BMP signaling pathway, an ...

Chemotherapy reshapes gut bacteria in ways that send powerful signals throughout the body. These signals reprogram immune cells, making organs like the liver more resistant to metastatic cancer.

The inner lining of the gut regenerates entirely every four to seven days, thanks to stem cells in the intestinal epithelium. Yet much remains shrouded in mystery regarding stem cells and what causes ...

The human immune system changes with age. Immune responses start to become less robust as people get older, which makes them more vulnerable to certain infections and diseases. However, immune system ...