Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein. Accordingly, Kinesin-5 ...

Simulations detail the mechanisms of kinesins that carry cargo inside cells. Scientists have determined the motor proteins respond best to strong forces and hardly at all to weak ones, even those ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...