C-type lectin receptors (CLRs) are a versatile family of transmembrane proteins pivotal in pathogen recognition and the initiation of immune responses. By recognising carbohydrate motifs on microbes, ...

People are exposed to millions of fungal spores every day, even potentially harmful ones like those from Aspergillus fumigatus. For most individuals, this constant exposure is harmless, as the immune ...

CAMBRIDGE, MA -- Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work ...

Dcir recognizes Aspergillus fumigatus hyphae and dampens the degranulatory activity of neutrophils. Without Dcir, neutrophils show enhanced fungicidal activity, and the host’s ability to eliminate the ...