NLRP3 inflammasome is a key component of the innate immune system. As a major mediator of inflammation, NLRP3 plays a central role in the pathogenesis of neurodegenerative and autoinflammatory ...

Interleukin 37 (IL-37) is a fundamental anti-inflammatory cytokine within the IL-1 family. Synthesis of IL-37 is induced in immune and non-immune cells following inflammatory stimuli. Intracellularly, ...

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

Life's Essential 8 (LE8) and Life's Crucial 9 (LC9) from the American Heart Association are industry-accepted metrics that summarize overall cardiovascular health. A new study documents inverse ...

In IAV-infected wild-type AECII, ELOVL5 promoted inflammation resolution and cell proliferation through both regulating lipid metabolism (promoting PUFAs generation while decreasing eicosanoid levels) ...

The buzzy term gets blamed for many diseases. But it isn’t all bad. Credit...Pete Gamlen Supported by By Nina Agrawal Illustrations by Pete Gamlen Inflammation has become a bit of a dirty word. We ...

Study identifies inflammatory signatures linked to cognitive decline in Alzheimer’s disease, supporting biomarker-guided ...

Chinese researchers have revealed the key role of iron in initiating allergic airway inflammation. The study, which was ...

Inflammation is an immune response from the body’s immune system when there is a perceived injury or infection. When injured, inflammation causes the area to become red and swell due to a large number ...