Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...

Researchers at the University of Hawaiʻi at Mānoa have developed new mouse models to study a key male fertility gene, ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

The new molecules selectively reduced inflammatory signaling in human immune cells without affecting other immune pathways. Treatment with the molecules also reduced inflammation in mice with the ...

Research led by the SickKids Research Institute in Toronto and the University of Pennsylvania, has found that immune-related ...

Scientists have discovered a method of helping human stem cells thrive in an animal embryo—a key development in efforts to grow human organs in animals for medical transplants. A study by UT ...

A research team led by Associate Professor Hirofumi Nishizono and graduate student Masaki Kato from the Research Support ...