The “atrofish” reveals early triggers of sarcopenia and links muscle loss to nerve degeneration, establishing a platform for comparative research on muscle aging and potential therapies As people age, ...
Wild type control zebrafish larvae, left, show robust locomotion. Transgenic “atrofish” pioneered by Romain Madelaine, Ph.D., right, are treated with a triggering chemical to mimic muscle decline ...
As people age, muscles naturally lose mass and strength, a condition known as sarcopenia. The decline can make everyday activities harder and increases the risk of falls, disability, and early death.