In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins with specific functions, from antibodies to blood clotting agents, by using ...
According to textbooks, proteins work by folding into stable 3D shapes that, like Lego blocks, precisely fit with other biomolecules. Yet this picture of proteins, the "workhorses of biology," is ...
A new research initiative, AI Biodesign, will build novel biomolecules that don’t currently exist in nature. The AI-designed ...
For decades, scientists have relied on structure to understand protein function. Tools like AlphaFold have revolutionized how researchers predict and design folded proteins, allowing for new ...
Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches ...
Just a decade ago, experimental work by Guerrier, Flayeux, and Boschetti demonstrated the ability of sodium chloride (NaCl) gradients on hydroxyapatite (HA) to remove aggregates from IgG preparations.