Engagement of intracellular targets is often critical to drug mechanisms. Establishing a target engagement (TE) profile is an important step in small- molecule drug discovery as well as chemical probe ...
The last two decades have witnessed the steady growth of the protein drug market. As original recombinant products come off patent, generics/ biosimilars are also beginning to be manufactured. The ...
This article highlights the use of SCIEX ZenoTOF 8600 equipment for high-throughput quantitative proteomics analysis. Using improved separations with the Evosep One system and high-sensitivity ...
Phase II Trial of TAS-102 in Colorectal Cancer Patients With Circulating Tumor DNA-Defined Minimal Residual Disease After Adjuvant Therapy: INTERCEPT-TT A multiplex QIF assay was optimized on tissue ...
Analyzing protein expression in biological samples has traditionally been challenging and often poorly reproducible. While methods like western blot have been around for decades, Simple Western™ ...
Proteomics is a research field focusing on the large-scale study of proteins in biological contexts. The goal is to describe various biological questions related to aging, drug treatment, disease, and ...
Qualitative analysis serves as the foundation for compound identification. It focuses primarily on determining the elemental composition and structure of analytes within a sample. Identifying the ...
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