Cancer tumors hijack the vagus nerve to communicate with the brain, triggering a hormonal response that suppresses the immune system.

Despite progress in cancer biology, deciphering the spatial architecture of the tumor microenvironment remains a challenge. Traditional approaches lack the resolution to map cell-type-specific gene ...

Existing oncology therapeutics are either so specific they can target only part of a tumor, or so generalized they kill healthy tissue. A new “Tumor Activated Therapy™” in development at the small ...

Scientists have identified a hidden barrier that prevents immunotherapy from working against a rare liver cancer. Immunotherapy, which activates the body’s own immune system to kill cancer cells, has ...

Liquid biopsies, which test body fluids that contain cancerous material, including circulating tumor DNA (ctDNA), are a noninvasive way to learn about a cancer's biology. However, technological ...

Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed a score ...

Immunotherapy—which activates the body's own immune system to kill cancer cells—has not worked well against a rare and fatal liver cancer, but a new study finds an existing FDA-approved drug may allow ...

Early-onset colorectal cancer (EO CRC) is marked by unusually stiff, fibrotic colorectal tissue that actively promotes tumor growth, according to a new study that points to biomechanical remodeling as ...

This article explores how tissue-based companion diagnostics leveraging immunohistochemistry approaches will help to select patients for targeted cancer treatments.