A visual depiction of the formation process of hybrid exosomes loaded with therapeutic cargo, achieved simply by mixing cubosomes and exosomes. The figure illustrates the actual preparation method, ...
Exosomes, naturally derived vesicles responsible for intercellular communication, are emerging as next-generation drug delivery systems capable of transporting therapeutics to specific cells. However, ...
Mn 2+ assembles with PTEN mRNA through weak forces rather than electrostatic interactions, facilitating reversible and efficient cellular mRNA release with a rational absolute binding free energies ...
The mRNA discovery is further enhanced with target-specific mRNA synthesis, particularly focused on enzyme receptors and growth factor receptors. By customizing mRNA payloads that encode for key ...
Lonza to support cGMP manufacturing of RION’s Purified Exosome Product™ (PEP™), a platelet-derived exosome-based drug candidate for chronic wound care and tissue regeneration Collaboration leverages ...