Ion Exchange Chromatography Principle, Procedure & Applications
Ion Exchange Chromatography Principle, Procedure & Applications
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🧪 Ion exchange chromatography (IEX) is a separation technique that exploits the interaction between charged molecules and oppositely charged stationary phases to separate and purify compounds based on their net charge. Hence, IEX separations are routinely used for quality attribute profiling of #biopharmaceuticals, be it charge variant analysis of monoclonal #antibodies (#mAbs) and recombinant #proteins or determining the capsid fill state of viral vectors 🧬 for gene therapy. Yet, challenges l
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